Gene drug breakthrough offers hope of a cure for aggressive form of heart failure

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• Pioneering drug edits DNA in the body without any tissue having to be removed
• Just a single dose was required for the twelve patients treated in the UK trial  
• May be possible to use same technology for blindness, high cholesterol and HIV

A pioneering gene-editing drug has raised hopes of a cure for an aggressive form of heart failure that affects up to 50,000 British patients, landmark UK trial results have shown.

This is the first time such a drug – which edits DNA in the body without any tissue having to be removed – has yielded results in patients. Just a single dose was required.

The breakthrough, announced yesterday at the American Heart Association conference in Chicago, throws open the doors to tackling a host of conditions in a similar way, including blindness, high cholesterol and even HIV.